Computational biology / plant science / bioinformatics

Alen Zimic-Sheen

Alen Zimic / Alen Zimic Sheen

About

Background

I'm an upcoming Computational Biology PhD student at Cornell University, beginning in August 2026 with support from the SUNY Fellowship. I am interested in how computation can help connect plant genes, metabolites, microbes, and environmental stress into clearer biological stories.

I come from Peru, where my first research experiences grew from field-facing questions about agriculture, soil microbes, environmental biotechnology, and public health. That background still shapes how I think about computational biology: useful tools should stay connected to biological systems, local context, and the people who work with them.

At Cornell’s Moghe Lab, I work on data-mining approaches for plant metabolites and gene-function discovery. Before that, I worked across plant-microbe systems, environmental biotechnology, metagenomics, protein modeling, and synthetic biology projects in Peru and at UC Berkeley/USDA.

Experience

Current and recent work

Ithaca, NY

Aug 2025 - Current

Laboratory Technician

Plant Science Department, Cornell University - PI: Gaurav Moghe, PhD

Current focus

Building computational workflows in the Moghe Lab as part of the C-SPIRIT research team, connecting uncharacterized plant metabolites with genes, tissues, species, and stress-related traits.

  • LLMs
  • Plant Metabolites
  • Graph Neural Networks
  • Python

Jan 2025 - May 2025

Visiting Student Researcher

Plant Gene Expression Center, UC Berkeley - USDA - PI: Devin Coleman-Derr, PhD

Studied drought-associated plant-microbe interactions in sorghum, connecting greenhouse work, RNA extraction, phenotyping, and Streptomyces genomics.

Jun 2021 - Jan 2025

Research Assistant

Bioinformatics and Molecular Biology Laboratory, UPCH - PIs: Mirko Zimic, PhD and Patricia Sheen, PhD

Worked across pathogen bioinformatics, antigen modeling, metagenomics, and molecular biology platforms in a lab spanning health and environmental applications.

Jan 2024 - Jan 2025

Bachelor's Thesis Researcher

Laboratory of Functional Genomics, UPCH - PI: Luis De-Stefano, PhD

Built a field-to-sequencing workflow to study how biofertilizer treatments may shift avocado rhizosphere microbiomes.

Sep 2023 - Jan 2025

Research Assistant

Laboratory of Andean-Amazonian Chemistry of Life, UPCH - PI: Denis Castillo, PhD

Developed and analyzed biodegradable hydrogels as a controlled-release approach for agricultural nitrogen management.

Publications

Articles and reviews

Full CV
2025 Enrichment of root-associated Streptomyces strains in response to drought is driven by diverse functional traits and does not predict beneficial effects on plant growth PLOS Biology A strain-level view of drought-enriched Streptomyces in sorghum roots, showing that enrichment and plant-growth benefit do not map cleanly onto the genus as a whole. 2026 Rapid and cost-effective fabrication of microfluidic chips with resin 3D printing Progress in Additive Manufacturing A practical evaluation of resin 3D printing as a lower-cost route for prototyping PDMS microfluidic templates. 2025 A simple and low-cost electrode based on Nafion-stabilized silver nanoparticles supported on FTO for the electrochemical determination of Pb(II) and Cu(II) PLOS ONE A low-cost electrochemical sensing approach for detecting lead and copper ions using silver nanoparticles stabilized on FTO. 2023 An Open Hardware Bioprinter Part I: A bioextruder with a peristaltic pump approach IEEE Xplore An open-hardware bioextrusion design built around a peristaltic pump architecture for accessible bioprinting. 2023 Multiantigen print immunoassay (MAPIA) for the diagnosis of neurocysticercosis: a single-center diagnostic optimization and accuracy study in Lima, Peru Journal of Clinical Microbiology A diagnostic optimization study evaluating a multiantigen print immunoassay for neurocysticercosis in a Lima clinical setting.

Projects

Code and research builds

Apr 2026

RoPE Visualized

Interactive rotary embeddings teaching demo

A static, dependency-free visual demo for teaching rotary positional embeddings, including real RoPE formulas and cosine-similarity comparisons.

  • Transformers
  • LLMs
  • Visualization

Apr 2026

Mentoring Workspace

Mentor-mentee collaboration tracker

Built for REU mentoring, this shared workspace helps mentor-mentee teams track notes, tasks, deadlines, and Google Docs/Sheets sync.

  • Mentoring
  • Research Training
  • Google Apps Script

Jun 2024

PupilTrackingDiagnosis

Computer vision for saccadic eye movement analysis

A small computer-vision workflow for tracking eye movement responses from video and extracting interpretable motion features.

  • Computer Vision
  • Python
  • Biomedical Signals

Apr - Jun 2024

AutismSketchClassifier

Sketch feature classification with deep learning embeddings

A machine-learning experiment using learned image embeddings to classify sketch-derived visual features.

  • ResNet
  • KNN
  • Machine Learning

2026

Plant AI Training Repository

A practical AI tools guide for plant scientists

A companion repository for the Plant Cell review, collecting relevant AI tools and learning resources for plant scientists.

  • Plant Science
  • AI Tools
  • Training Resource

Education

Training

Beginning August 2026

PhD in Computational Biology

Cornell University

Incoming PhD student in Computational Biology at Cornell University, funded by the SUNY Fellowship.

2019 - 2024

B.Sc. in Environmental Engineering

Universidad Peruana Cayetano Heredia, Lima, Peru

Graduated with a GPA of 3.86 and ranked second in order of merit across the Environmental Engineering program.

Recognition

Funding, honors, and talks

Selected support, awards, presentations, and public science.

Community

Scientific service

Selected roles in training, synthetic biology, and student leadership.

Nov 2025 - Present Cornell I-CIPS student co-lead Student co-lead for Cornell's Initiative for Computational Innovation in Plant Sciences.
Oct 2024 - 2026 iGEM Engineering Plan Committee member Nearly two years supporting the iGEM Engineering Plan Committee, with emphasis on plant-based synthetic biology projects.

Notes

Field notes and short writing

A small blog-style space for updates when there is something worth writing down.

Contact

Open to talk